Table 3.
Two-Point LOD Scoresfor Allele Frequencies from |
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Control Population |
Pedigree |
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Chromosome | Marker Region | Interval(cM) | Peak Marker | Allele-SharingP Valuea | DominantModel | RecessiveModel | DominantModel | RecessiveModel |
1 | D1S214–D1S 450 | 0–6.6 | D1S450 | .0459 | 1.59 | 1.11 | NS | NS |
1 | D1S1655–D1S1551 | 97.6–109.8 | D1S2841 | .0137 | 1.60 | .97 | NS | NS |
2 | D2S162–D2S149 | 9.1–23.0 | D2S287 | .0047 | 1.86 | 1.52 | 2.08 | 1.63 |
13 | … | … | D13S1306 | .0631 | 1.90 | 1.95 | 1.99 | 2.07 |
13 | … | … | D13S173 | NS | 1.31 | 1.23 | NS | NS |
15 | … | … | D15S205 | NS | 3.13 | 3.26 | NS | NS |
17 | D17S831–D17S1298 | 5.9–10.1 | D17S938 | NS | 2.32 | 2.59 | NS | NS |
Note.— NS = not significant (P>.05).
Allele sharing statistics obtained with SIMWALK2 (Sobel and Lange 1996).