Table 2. Antimicrobial activity of HBD-1 and-3 analogs.
LC (µM)
|
MFC (µM) | |||
---|---|---|---|---|
E. coli | P. aeruginosa | S. aureus | C. albicans | |
Phd-1a | 15 | - | 20 | 18 |
Phd-3a | 17 | - | 17 | 16 |
HC-1(R) | 5 | 5 | 5 | 2.5 |
[D]HC-1(R) | 5 | 5 | 5 | 5 |
[D]HC-3(R) | 2.5 | 2.5 | 2.5 | 2.5 |
The values reported are average of three independent experiments done in duplicates. Variations observed were <5%. a Values represented are from [23],- denotes not determined.