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. 2013 Sep 27;8(9):e76234. doi: 10.1371/journal.pone.0076234

Figure 2. NR4A2 activates NBRE promoter elements.

Figure 2

A: Gastrin-induced NBRE-luc activation. Data represent one of two biological replicas. B: The effect of NR4A2 siRNA on gastrin-induced NBRE activation. Data represent mean ± SEM of four biological replicas (** p<0.01, * p=0.1). C-D: Effect of specific inhibitors of PKA (H-89, 10µM), PI3K (LY 294002, 10µM) or PKC (GF 109203x, 3.5µM) on (C) gastrin-induced NR4A2 gene expression and (D) gastrin-induced NBRE activation. Data represent one of three biological replicas; mean ± SD of six technical replicas.