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. 2013 Sep 27;8(9):e70878. doi: 10.1371/journal.pone.0070878

Table 1. Demographic and clinicopathological data of Ovarian Cancer samples (Training set and independent validation set) and Normal Ovarian samples.

1st portion of Cases (n = 33) 2nd portion of cases (n = 24) Training set (Total) Controls(n = 13)
Age at diagnosis
Median 57 56 57 46
Range 23–79 37–77 23–77 40–55
Follow-up (months)
Median 24 37 30.5
Range 0–228 13–79 0–228
Race
Caucasian 24 24 48 0
African-american 8 0 8 0
Hispanic 0 0 0 13
Unknown 1 0 1 0
Tumor type
EOC* 33 18 51
Germ cell tumor 0 1 1
Metastasis 0 4 4
Unknown 0 1 1
Histology
Serous-papillary 33 11 44
Endometrioid 0 4 4
Mucinous 0 2 2
Undifferentiated 0 1 1
Unknown 0 6 6
Stage
I 15 6 21
II 1 4 5
III 14 12 26
IV 3 1 4
Unknown 0 1 1
Grade
Borderline 12 0 12
G1 0 2 2
G2 8 5 13
G3 13 12 25
GX** 0 1 1
Unknown 0 4 4
Chemotherapy
Yes 11 23 34
No 9 0 9
Unknown 13 1 14
Type of chemotherapy
Platinum/taxol after surgery 0 18 18
Platinum/taxol before and after surgery 0 6 6
Unknown 33 0 33
Recurrence
Yes 4 14 18
No 0 10 10
Unknown 29 0 29
Metastasis
Yes 1 0 1
No 32 0 32
Unknown 0 24 24
Smoking
Smoker 2 5 7
Non-smoker 16 19 35
Unknown 15 0 15
Alcohol
Current 6 2 8
No 12 22 34
Unknown 15 0 15
B. Validation set
Ovarian cancer patients n = 372
Age at diagnosis
Median 61
Range 21–89
Follow-up time (months)
Median 30
Range 0–234
Unknown n = 1
Histology n %
Serous 227 61%
Mucinous 43 12%
Endometroid 39 10%
Clear cell 18 5%
Adenocarcinoma 13 3%
Other 31 8%
Unknown 1 0%
Grade
Borderline 5 1%
I 57 15%
II 101 27%
III 154 41%
Undifferentiated 19 5%
Unknown 36 10%
FIGO Stage
I 67 18%
II 30 8%
III 224 60%
IV 51 14%
Residual disease after surgery
<2 cm 184 49%
>2 cm 160 43%
Unknown 28 8%
Chemotherapy
No chemotherapy 56 15%
Platinum-containing 173 47%
Platinum and taxane containing 105 28%
Other 30 8%
Unknown 8 2%
316
Borderline tumors n = 17
Age at diagnosis
Median 50
Range 19–77
Unknown (n = 5)
Cystadenoma n = 18
Age at diagnosis
Median 30
Range 26–55
Unknown (n = 15)
*

Epithelial ovarian cancer ** Grade cannot be assessed.