Table 4. Cox proportional hazards model of variables predicting decreased overall survival.

UNIVARIATE ANALYSIS
Variables
	P value	HR	95% C.I.
Age (>61)	0.001	1.57	1.19	2.06
Histology (serous)	<0.001	2.46	1.74	3.48
Grade (III/undifferentiated)	<0.001	1.91	1.42	2.56
Stage (III/IV)	<0.001	8.22	4.91	13.76
Residual disease after surgery (>2 cm)	<0.001	4.73	3.47	6.44
PGP9.5 methylated	0.004	0.59	0.42	0.84
VGF methylated	0.028	0.73	0.55	0.97
MULTIVARIATE ANALYSIS
Covariate
PGP9.5 methylated	0.524	1.15	0.74	1.80
Age (continuous)	0.378	1.01	0.99	1.02
Histology (serous)	0.671	1.10	0.70	1.73
Grade (III/undifferentiated)	0.769	1.05	0.75	1.48
Stage (III/IV)	<0.001	4.56	2.26	9.22
Residual disease after surgery (>2 cm)	<0.001	2.70	1.84	3.97
Covariate
VGF methylated	0.005	0.62	0.44	0.87
Age (continuous)	0.215	1.01	1.00	1.02
Histology (serous)	0.509	1.16	0.74	1.81
Grade (III/undifferentiated)	0.529	1.12	0.79	1.58
Stage (III/IV)	<0.001	4.04	2.02	8.11
Residual disease after surgery (>2 cm)	<0.001	2.76	1.88	4.04
Covariate
VGF methylated	0.014	0.69	0.51	0.93
Stage (III/IV)	<0.001	4.67	2.67	8.16
Residual disease after surgery (>2 cm)	<0.001	2.79	2.00	3.88

BOLD P≤.05 was considered statistically significant.