Table 3. Comparison of prevalence of nasopharyngeal carriage of any pneumococcal carriage (Any type), vaccine serotypes (VT), non-vaccine serotypes (NVT) and serotypes 6A and 19A in different cross-sectional surveys in partly vaccinated villages.
| CSS-4 vs Baseline | CSS-4 vs CSS-1 | CSS-4 vs CSS-2 | CSS-4 vs CSS-3 | ||||||
| Serotype group | Age Group (years) | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value |
| Any type | 2.5-<5 | 0.18 (0.07,0.46) | <0.001 | 0.27 (0.10,0.71) | 0.008 | 1.26 (0.61,2.60) | 0.538 | 0.69 (0.25,1.89) | 0.467 |
| 5-<15 | 0.15 (0.09,0.25) | <0.001 | 0.53 (0.32,0.88) | 0.014 | 1.02 (0.62,1.67) | 0.950 | 0.52 (0.28,0.97) | 0.040 | |
| > = 15 | 0.154 (0.10,0.24) | <0.001 | 0.80 (0.49,1.31) | 0.373 | 0.80 (0.50,1.30) | 0.367 | 0.49 (0.24,1.02) | 0.056 | |
| All ages | 0.20 (0.15,0.26) | <0.001 | 0.76 (0.56,1.02) | 0.071 | 1.11 (0.82,1.49) | 0.494 | 0.60 (0.40,0.89) | 0.011 | |
| VT | 2.5-<5 | 0.15 (0.07,0.33) | <0.001 | 0.58 (0.23,1.48) | 0.253 | 0.42 (0.18,1.01) | 0.052 | 0.35 (0.12,1.03) | 0.057 |
| 5-<15 | 0.21 (0.10,0.42) | <0.001 | 1.27 (0.54,2.99) | 0.577 | 1.21 (0.53,2.76) | 0.657 | 0.68 (0.28,1.63) | 0.388 | |
| > = 15 | 0.02 (0.003,0.18) | <0.001 | 0.12 (0.01,0.96) | 0.046 | 0.15 (0.02,1.23) | 0.077 | 0.04 (0.01,0.37) | 0.004 | |
| All ages | 0.18 (0.11,0.28) | <0.001 | 0.85 (0.49,1.47) | 0.558 | 0.79 (0.46,1.35) | 0.383 | 0.42 (0.23,0.76) | 0.004 | |
| NVT | 2.5-<5 | 1.02 (0.55,1.89) | 0.955 | 0.47 (0.22,1.01) | 0.054 | 2.19 (1.09,4.40) | 0.028 | 1.43 (0.60,3.41) | 0.413 |
| 5-<15 | 0.42 (0.26,0.67) | <0.001 | 0.48 (0.29,0.80) | 0.004 | 0.96 (0.58,1.59) | 0.869 | 0.63 (0.35,1.14) | 0.129 | |
| > = 15 | 0.29 (0.19,0.44) | <0.001 | 0.94 (0.57,1.56) | 0.825 | 0.90 (0.55,1.48) | 0.692 | 0.67 (0.31,1.43) | 0.302 | |
| All ages | 0.44 (0.33,0.58) | <0.001 | 0.75 (0.55,1.01) | 0.055 | 1.18 (0.87,1.60) | 0.274 | 0.78 (0.52,1.15) | 0.211 | |
| Serotype 6A (VT) | 2.5-<5 | 0.79 (0.24,2.62) | 0.702 | 0.72 (0.19,2.77) | 0.638 | 0.63 (0.18,2.23) | 0.474 | 0.34 (0.08,1.47) | 0.148 |
| 5-<15 | 3.61 (0.98,13.34) | 0.054 | 9.86 (1.16,83.63) | 0.036 | 2.59 (0.71,9.49) | 0.150 | 4.85 (0.56,41.7) | 0.151 | |
| > = 15 | 0.16 (0.02),1.29) | 0.085 | Infinite (---)a | 0.463 | 0.60 (0.05,6.73) | 0.678 | 0.21 (0.01,3.59) | 0.283 | |
| All ages | 1.10 (0.54, 2.22) | 0.792 | 3.09 (1.09,8.76) | 0.034 | 1.50 (0.66,3.40) | 0.332 | 1.09 (0.40,2.95) | 0.860 | |
| Serotype 19A (NVT) | 2.5-<5 | 0.62 (0.22,1.80) | 0.381 | Infinite (---)a | 0.051 | 4.28 (0.50,36.42) | 0.183 | 0.58 (0.12,2.78) | 0.499 |
| 5-<15 | 0.51 (0.11,2.46) | 0.402 | 1.48 (0.20,10.73) | 0.697 | 0.80 (0.14,4.48) | 0.803 | 0.56 (0.09,3.45) | 0.531 | |
| > = 15 | 1.03 (0.19,5.48) | 0.968 | Infinite (---)a | 0.214 | 1.53 (0.21,11.13) | 0.673 | Infinite (---)a | 1.000 | |
| All ages | 0.83 (0.39,1.77) | 0.637 | 6.22 (1.36,28.45) | 0.018 | 1.90 (0.72,5.01) | 0.192 | 0.99 (0.35,2.75) | 0.983 | |
a
It was not possible to fit the model.
OR's were calculated ignoring clustering and p-values using Fisher's exact test.