Table 4. Comparison of prevalence of nasopharyngeal carriage of any pneumococcal carriage (Any type), vaccine serotypes (VT), non-vaccine serotypes (NVT) and serotypes 6A and 19A in different cross-sectional surveys in wholly vaccinated villages.
| Serotype group | Age group (years) | CSS-4 vs Baseline | CSS-4 vs CSS-1 | CSS-4 vs CSS-2 | CSS-4 vs CSS-3 | ||||
| OR (95%CI) | p-value | OR 95%CI | p-value | OR (95%CI) | p-value | OR (95%CI) | p-value | ||
| Any | 2.5-<5 | 0.28 (0.13,0.58) | 0.001 | 0.27 (0.12,0.61) | 0.002 | 1.58 (0.83,3.01) | 0.165 | 0.49 (0.18,1.37) | 0.173 |
| 5-<15 | 0.07 (0.04,0.12) | <0.001 | 0.25 (0.15,0.41) | <0.001 | 0.55 (0.33,0.93) | 0.024 | 0.21 (0.12,0.38) | <0.001 | |
| > = 15 | 0.16 (0.11,0.24) | <0.001 | 0.46 (0.29,0.73) | 0.001 | 0.75 (0.47,1.20) | 0.225 | 0.56 (0.29,1.09) | 0.088 | |
| All ages | 0.17 (0.13,0.22) | <0.001 | 0.46 (0.35,0.61) | <0.001 | 0.99 (0.74,1.32) | 0.924 | 0.45 (0.31,0.64) | <0.001 | |
| VT | 2.5-<5 | 0.08 (0.04,0.18) | <0.001 | 0.42 (0.18,1.02) | 0.057 | 0.35 (0.14,0.85) | 0.021 | 0.49(0.14,1.78) | 0.280 |
| 5-<15 | 0.14 (0.06,0.33) | <0.001 | 0.70 (0.25,1.93) | 0.489 | 2.80 (0.68,11.48) | 0.154 | 0.91(0.29,2.81) | 0.870 | |
| > = 15 | 0.03 (0.00,0.15) | <0.001 | 0.10 (0.00,0.66) | 0.008 | 0.30 (0.01,3.04) | 0.383 | Inf (---)a | 1.000 | |
| All ages | 0.13 (0.07,0.21) | <0.001 | 0.49 (0.27,0.89) | 0.019 | 0.90 (0.47,1.73) | 0.75 | 0.84 (0.38,1.82) | 0.653 | |
| NVT | 2.5-<5 | 1.37 (0.78,2.38) | 0.272 | 0.66 (0.35,1.22) | 0.184 | 2.27 (1.21,4.26) | 0.011 | 0.81 (0.33,1.95) | 0.638 |
| 5-<15 | 0.19 (0.12,0.31) | <0.001 | 0.25 (0.15,0.43) | <0.001 | 0.48 (0.2830.82) | 0.007 | 0.22 (0.12,0.39) | <0.001 | |
| > = 15 | 0.28 (0.19,0.42) | <0.001 | 0.55 (0.35,0.87) | 0.010 | 0.80 (0.49,1.28) | 0.346 | 0.56 (0.29,1.09) | 0.087 | |
| All ages | 0.38 (0.29,0.49) | <0.001 | 0.53 (0.40,0.70) | <0.001 | 0.98 (0.73,1.31) | 0.908 | 0.47 (0.33,0.67) | <0.001 | |
| Serotype 6A (VT) | 2.5-<5 | 0.25 (0.08,0.80) | 0.019 | 0.51 (0.13,1.97) | 0.330 | 0.55 (0.13,2.28) | 0.410 | 0.43 (0.07,2.59) | 0.359 |
| 5-<15 | 0.51 (0.14,1.82) | 0.300 | 1.49 (0.29,7.63) | 0.635 | 4.54 (0.46,45.05) | 0.196 | 1.51 (0.24,9.37) | 0.656 | |
| > = 15 | 0.00 (0.00,0.57) | 0.008 | 0.00 (0.00,0.65) | 0.018 | -b | - | -b | - | |
| All ages | 0.32 (0.14,0.72) | 0.006 | 0.53 (0.21,1.31) | 0.170 | 1.57 (0.49,4.99) | 0.447 | 0.94 (0.27,3.27) | 0.927 | |
| Serotype 19A (NVT) | 2.5-<5 | 0.81 (0.22,2.90) | 0.742 | 1.62 (0.30,8.65) | 0.574 | Infinite (---)a | 0.161 | 0.16 (0.04,0.67) | 0.013 |
| 5-<15 | 2.37 (0.76,7.32) | 0.135 | 4.40 (0.86,22.42) | 0.074 | Infinite (---)a | 0.003 | 0.79 (0.26,2.37) | 0.677 | |
| > = 15 | 0.00 (0.00,2.18) | 0.319 | 0 (0., ---) | 1.000 | 0 (0, ---) | 1.000 | 0 (0, ---) | 0.229 | |
| All ages | 1.28 (0.58,2.82) | 0.542 | 2.393 (0.82,6.99) | 0.111 | 11.50 (1.47,89.83) | 0.020 | 0.41 (0.18,0.93) | 0.033 | |
a
It was not possible to fit the model. OR's were calculated ignoring clustering and p-values using Fisher's exact test.
b
Values could not be calculated.