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. 2013 Sep 27;8(9):e74194. doi: 10.1371/journal.pone.0074194

Figure 1. Effect of streptochlorin on cytotoxicity and degranulation in RBL-2H3 cells.

Figure 1

(A) Streptomyces sp. (strain 04DH110) and its molecular structure. (B) Cell viability assay of indicated concentrations of streptochlorin in RBL-2H3 cells measured by MTT assay. (C) Degranulation was determined by measuring β-hexosaminidase activity in RBL-2H3 cells. The values indicate mean ± standard error of the mean (n = 3), from three independent experiments by one-way analysis of variance followed by Dunnett's multiple comparison test. ** P<0.01 and *** P<0.001 significant difference compared with the DNP-HSA only treated group. Str, streptochlorin; DNP-HSA, dinitrophenyl-human serum albumin.