Skip to main content
. 2013 Sep 27;8(9):e74194. doi: 10.1371/journal.pone.0074194

Figure 5. The effect of streptochlorin on DNFB-induced allergic dermatitis.

Figure 5

(A) The experimental scheme. (B) Balb/c mice (n = 5) were sensitized with DNFB with the indicated amount of streptochlorin. Ear thickness was determined on the indicated dates. (C) Ear lobe tissue homogenates were prepared from mice in each group, and the lysates were measured by an MPO assay. (D) Histologic images of the ear lobes of mice in each group stained with hematoxylin (upper panel) and toluidine blue (lower panel) are shown. Dexamethasone was used as a positive control. The gray line means a boundary of dermis and epidermis, and infiltrated immune cells (arrowhead) and mast cells (arrow) were indicated. The values indicate mean ± standard error of the mean from three independent experiments by one-way analysis of variance followed by Dunnett's multiple comparison tests. * P<0.05 and *** P<0.001 significant difference from DNFB only treated group. Str, streptochlorin; Dex, dexamethasone.