Table 3.
Dynamic alteration of liver insulin-like growth factor-I receptor expression in hepatocarcinogenesis n (%)
| Group | n | Positive | P value |
IGF-IR intensity |
Nemenyi test | P value | |||
| - | + | ++ | +++ | ||||||
| Control | 12 | 0 (0.0) | 12 | 0 | 0 | 0 | |||
| Degeneration | 18 | 9 (50.0)1 | 0.004 | 9 | 4 | 4 | 1 | 13.7161 | < 0.050 |
| Precancerosis | 9 | 8 (88.9)1 | < 0.001 | 1 | 3 | 2 | 3 | 16.2291 | < 0.001 |
| HCC | 9 | 9 (100)1 | < 0.001 | 0 | 1 | 5 | 3 | 16.2991 | < 0.001 |
1
Compared with the control group by the Kruskal-Wallis test (HC = 25.5149, P < 0.001). IGF-IR: Insulin-like growth factor-I receptor; HCC: Hepatocellular carcinoma.