Fig. 1.

a Representation of the Sholl analysis. Quantification can be made by superimposing a series of concentric circles of gradually increasing radius around the soma of the neurone. Branching points, intersections and endings can be calculated with this method. b Example of a graphical representation of the dendritic branching pattern of a neurone. c Dendrite of a cortical pyramidal neurone with its dendritic spines (Golgi-Cox method). d One possible way of analysing the relative fibre densities is to count the number of fibre fragments that intercept grid-points within a counting frame. e Two fibres intercept grid-points (upper left). Since the analysis is conducted on two dimensional images, we cannot determine whether these fibre fragments belong to the same fibre or to different fibres