Table 1.

One-pot synthesis of alkynyl indoles A and B

Entry	M	Y1	Y2	Z1X	Z2	Yield (%)	A:B
1	M1	CH2	CH2	pClPhSO2Cl	4-Br	49	0.56:1
2	M2	CH2	CH2CH2	MeOCOCl	3,5-diMe	55	1.8:1
3	M3	CH2	ophenylene	AcCl	ophenylene	60	1.1:1
4	M4	CH2CH2	CH2	(CF3CO)2O	4-Cl	45	0.77:1
5	M5	CH2CH2	CH2CH2	pFPhCOCl	4-OMe	55	1.3:1
6	M6	CH2CH2	ophenylene	pBrPhSO2Cl	H	54	0.5:1
7	M1	CH2	CH2	pClPhCOCl	2-OMe	60	1:1
8	M2	CH2	CH2CH2	pClPhSO2Cl	H	83	0.4:1
9	M3	CH2	ophenylene	MeOCOCl	4-OMe	55	1.8:1
10	M4	CH2CH2	CH2	(CF3CO)2O	4-Me	70	1:1
11	M5	CH2CH2	CH2CH2	pFPhCOCl	ophenylene	60	1.3:1
12	M6	CH2CH2	ophenylene	pBrPhSO2Cl	3,5-diMe	65	0.28:1