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Serum 25(OH)D3 concentration in Cyp2r1 wild-type (WT), heterozygote (HET), and knockout (KO) mice (A) and in wild-type, Cyp27a1−/−, Cyp2r1−/−, and Cyp2r1−/−/Cyp27a1−/− mice (B) at 6, 10, and 14 wk of age measured by RIA. *P < 0.01 and ^P < 0.05, compared with wild-type groups of the same age.
