Fig. 6.

Involvement of the arachidonic acid cascade in H₂S effects. (A) SQ 29548 (1 µM), a TP receptor antagonist; indomethacin (1 µM), a COX inhibitor; and AACOCF3 (1 µM), a cPLA₂ inhibitor, significantly (*P < 0.05, **P < 0.01, ***P < 0.001) reduced the enhancing effects of l-Cys upon aggregation induced by TRAP-6 (2 µM) or (B) NaHS. Results are expressed as percent of maximal aggregation and calculated as mean ± SEM from five to eight healthy volunteers. Data were analyzed using one-way ANOVA followed by Bonferroni post-test.