FIG. 2.

The estimated glomerular filtration rate (eGFR) trajectory over time in those with a change in total cholesterol (TC) >50 mg/dl (increase in TC greater than 50 mg/dl) over approximately 3 years following ART initiation compared to those with a ≤50 mg/dl change. The comparison of eGFR trajectories between those with a change in high-density lipoprotein cholesterol (HDLc) <−5 mg/dl (a decrease in HDLc greater than 5 mg/dl) versus ≥−5 mg/dl is also shown. The average eGFR value at the pre-ART visit was approximately 100 ml/min/1.73 m² and the decrease in eGFR from that value based on the estimated slopes from the piecewise linear models is shown for the exposure groups.