Table 1.
Baseline characteristics | Included N=365 | Excluded N=1158 | pa |
---|---|---|---|
Age [years; median (IQR)] | 42 (38–48) | 42 (37–48) | 0.329 |
BMI [kg/m2; median (IQR)] | 24 (23–27) | 24 (22–27) | 0.709 |
Nadir CD4 [cells/ml; median (IQR)] | 249 (154–353) | 269 (143–397) | 0.154 |
Black | 16% | 31% | <0.001 |
ARV naive | 39% | 47% | 0.012 |
Pre-ART high blood pressure | 69% | 56% | <0.001 |
Statin use history | 9% | 9% | 0.839 |
Smoking history | 71% | 74% | 0.363 |
PI-based initial ART regimen | 70% | 43% | <0.001 |
Pre-ART serum creatinine [mg/dl; median (IQR)] | 0.9 (0.8–1.0) | 1.0 (0.9–1.1) | 0.179 |
Pre ART eGFR [ml/min/1.73 m2; median (IQR)] | 101 (89–110) | 96 (80–109) | 0.455 |
Pre-ART total cholesterol [mg/dl; median (IQR)] | 165 (143–193) | ||
Pre-ART HDL cholesterol [mg/dl; median (IQR)] | 38 (33–46) | ||
Pre-ART non-HDL cholesterol [mg/dl; median (IQR)] | 126 (105–154) | ||
Pre-ART triglycerides [mg/dl; median (IQR)] | 113 (73–154) |
Comparisons between the included and excluded samples were made using two-sample median tests and Chi-square tests.
Baseline characteristics (visit prior to HAART initiation) of HIV-infected men included in the current study and those who were eligible (initiated HAART from 1995 to 2011) but did not have available lipid level measurements pre- and post-HARRT.
IQR, interquartile range; BMI, body mass index; ARV, antiretroviral; ART, antiretroviral therapy; PI, protease inhibitor; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; HAART, highly active antiretroviral therapy.