FIG. 2.

Treg depletion can result in an increased or decreased CD4⁺ and CD8⁺ T cell proliferation in different subjects. The ratios between the percentage of cells proliferating in response to a peptide pool and to DMSO are shown for samples where the Treg depletion caused an increased (A, C) and decreased (B, D) CD4⁺ and CD8⁺ T cell proliferation, respectively. Each data pair represents the response to one peptide pool. N=number of responses. The p value was calculated by the Wilcoxon signed rank test.