Table 4.
Results of Simulation C: LCA model with misspecified prevalence function that depends on age only. True values of each diagnostic test parameter are compared to estimates from a misspecified covariate-augmented LCA model. There was no verification bias (α = 1). Each parameter estimate is presented as mean ± standard deviation (95% CI) of 1000 simulations. All values are reported as percents.
| True | Estimated | True | Estimated | True | Estimated | True | Estimated |
|---|---|---|---|---|---|---|---|
| S1 | S1 | C1 | C1 | S2 | S2 | C2 | C2 |
| 70 | 69 ± 19.1 (39,100) | 70 | 71 ± 2.6 (67,76) | 70 | 69 ± 18.9 (39,100) | 70 | 71 ±2.4 (67,76) |
| 70 | 67 ± 6.9 (55,82) | 70 | 71 ± 1.7 (68,75) | 95 | 88 ± 16.3 (51,100) | 95 | 96 ± 1.3 (94,99) |
| 70 | 67 ± 12.3 (48,99) | 95 | 95 ± 1.2 (93,98) | 70 | 67 ± 11.8 (47,97) | 95 | 96 ± 1.2 (93,98) |
| 85 | 80 ± 13.1 (58,100) | 85 | 86 ± 1.8 (83,90) | 85 | 81 ± 13 (58,100) | 85 | 86 ± 1.8 (83,90) |
| 85 | 81 ± 8.5 (67,100) | 85 | 86 ± 1.5 (83,89) | 95 | 91 ± 10.6 (67,100) | 95 | 96 ± 1.2 (93,98) |
| 85 | 82 ± 9.9 (64,100) | 95 | 95 ± 1.1 (93,98) | 85 | 83 ± 10 (65,100) | 95 | 95 ± 1.1 (93,98) |
| 95 | 88 ± 11.5 (64,100) | 70 | 71 ± 2.1 (68,76) | 95 | 88 ± 11.1 (66,100) | 70 | 71 ± 2.1 (68,76) |
| 95 | 90 ± 9.8 (70,100) | 85 | 86 ± 1.6 (83,89) | 95 | 90 ± 9.6 (70,100) | 85 | 86 ± 1.6 (83,89) |
| 95 | 92 ± 7.4 (76,100) | 95 | 95 ± 1 (94,97) | 95 | 93 ± 7.3 (77,100) | 95 | 95 ± 1 (94,97) |