Table 4.

Regions of event-related Stop BOLD activity (combined across groups) demonstrating significant group (Cocaine Dependent (CD), control), condition (punishment, neutral), or interaction effects. Phasic effects relate to event-related activity during stops, whilst tonic activity is calculated as a block average across punishment periods

Brain region	Volume (μl)	MNI coordinates			Phasic			Tonic
		x	y	z	Condition	Group	Group x Cond	Condition	Group
R Anterior Cingulate	1354	1	26	36	N>P	CD>C		P>N
L Putamen	722	−20	7	6	N>P	CD>C		P>N	CD>C
L Insula	418	−47	6	6	N>P	CD>C		P>N
L Inferior Frontal	401	−37	18	−14	N>P	CD>C
R Caudate	336	11	−1	16	N>P		*
R Precuneus	315	3	−64	41	N>P
L Superior Temporal	300	−54	−43	13	N>P
R Putamen	278	24	4	15	N>P	CD>C		P>N
L Middle Cingulate	238	−1	−12	45	N>P	CD>C	*		CD>C
R Inferior Frontal	156	29	30	−6	N>P	CD>C
L Cuneus	155	−3	−73	25	N>P			N>P
L Anterior Cingulate	144	−1	21	20		CD>C
R Superior Frontal	142	24	55	13		CD>C