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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Basic Res Cardiol. 2012 Nov 9;108(1):310. doi: 10.1007/s00395-012-0310-4

Figure 2.

Figure 2

Enhancement of EPC recruitment by angiogenic factors/chemokines: prominent role for MIF and VEGF. a, b Static adhesion of eEPCs on an endothelial layer under normoxic (a) and hypoxic (b) conditions (*p < 0.05 vs. isotype control, n = 3). c Chemotactic migration of calcein-labeled EPCs under normoxic conditions (*p < 0.05 vs. control, n = 3). d Chemotactic migration of calcein-labeled eEPCs under normoxic (black bars) and hypoxic (white bars) conditions towards MIF, VEGF, CXCL12, and CXCL1 (*p < 0.05 vs. control, § p < 0.05 vs. normoxia, # p < 0.05 vs. MIF under hypoxia; n = 3). e Transmigration of EPCs through an endothelial layer induced by MIF, VEGF, CXCL12, and CXCL1 (*p < 0.05 vs. control, n = 3). f Transmigration experiment as in e except that eEPCs were analyzed and normoxic versus hypoxic conditions compared for all chemokines/factors (*p < 0.05 vs. control, § p < 0.05 vs. normoxia, # p < 0.05 vs. MIF in hypoxia; n = 3)