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. 2013 Sep 30;3:54. doi: 10.3389/fcimb.2013.00054

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Copyright © 2013 Mansilla Pareja and Colombo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Escaping from autophagy recognition. Listeria monocytogenes uses an actin-based motility to escape from autophagy.ActAand PLCs are key bacterial factors to prevent bacteria targeting by autophagy. Recruitment to the bacterial surface of the actin nucleating proteins Arp2/3 and Ena/VASP, mediated by ActA, camouflages the bacteria from autophagic recognition. In addition, a member of the internalin family of proteins, InlK, a protein expressed at the surface of Listeria, and its host partner the Major Vault Protein (MVP) prevents L. monocytogenes from autophagic recognition.