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Dose response effects of MnTBAP treatment on lung MMP-2/TIMP-1 ratios levels in neonatal rats following intermittent hypoxia during hyperoxia (A, P14) and recovery in RA (B, P21). Data are presented as mean±SEM (n=18 pups per group, 9 males and 9 females). Animals were treated with IP injections of 1, 5, or 10 mg/kg MnTBAP on P0, P1 and P2 or equivalent volume saline (placebo controls).
