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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: Drug Dev Ind Pharm. 2011 Mar 30;37(6):673–684. doi: 10.3109/03639045.2010.535540

Table 2.

Influence copolymer composition and copolymer source on average particle size and the encapsulation efficiency of PDLLGA naltrexone (NTX)-loaded microspheres (average of two determinations).

Copolymers Particle size (μm) Encapsulation efficiency (%)
PDLLGA (90:10)Poly sci. (AN) 86.13 63.87
PDLLGA (90:10)Poly sci. (R) 58.41 58.82
PDLLGA (90:10)Bpi (AN) 64.37 68.55
PDLLGA (90:10)Bpi (R) 62.51 75.87
PDLLGA (65:35)Bpi (R) 67.57 65.07
PDLLGA (50:50)Bpi (R) 76.15 58.22

R = Regular NTX; AN = anhydrous NTX.