Table 1.
Bivariate Comparison of Baseline Factors with Week 12 Opioid Positive Urine Tests
| Intent to Treat Sample | |||||
|---|---|---|---|---|---|
| Urine − at Wk 12 | urine + Wk 12 | test statistic | p-value | ||
| Variable | n (%) mean (SD) | n (%) mean (SD) |
|||
| Treatment Group | 3.92 | 0.048 | |||
| BUP | 28 (60.9) | 46 (43.4) | |||
| DETOX | 18 (39.1) | 60 (56.6) | |||
| Baseline: Socio Demographics | |||||
| Age >= 18 | 0.282 | 0.596 | |||
| Yes | 37 (80.4) | 89 (84.0) | |||
| No | 9 (19.6) | 17 (16.0) | |||
| Gender | 3.540 | 0.060 | |||
| Female | 24 (52.2) | 38 (35.8) | |||
| Male | 22 (47.8) | 68 (64.2) | |||
| Race | 1.550 | 0.213 | |||
| Caucasian | 37 (80.4) | 75 (70.8) | |||
| Non-Caucasian | 9 (19.6) | 31 (29.2) | |||
| Employment 30 Days | 0.287 | 0.592 | |||
| Yes | 23 (50.0) | 58 (54.7) | |||
| No | 23 (50.0) | 48 (45.3) | |||
| Years of Education | 0.46 | 0.647 | |||
| 11.24 (1.5) | 11.11 (1.6) | ||||
| Baseline: Substance Abuse Characteristics | |||||
| Opioid Use 30 days | 2.515 | 0.284 | |||
| Heroin Only | 15 (32.6) | 45 (42.9) | |||
| Non-Heroin Opioids | 10 (21.7) | 26 (24.8) | |||
| Both | 21 (45.7) | 34 (32.4) | |||
| Opioid Use Lifetime | 0.437 | 0.804 | |||
| Heroin Only | 17 (37.0) | 43 (42.6) | |||
| Non-Heroin Opioids | 13 (28.3) | 27 (26.7) | |||
| Both | 16 (34.8) | 31 (30.7) | |||
| Cocaine Use 30 Days | 0.287 | 0.592 | |||
| Yes | 23 (50.0) | 48 (45.3) | |||
| No | 23 (50.0) | 58 (54.7) | |||
| Marijuana Use 30 Days | 0.829 | 0.363 | |||
| Yes | 33 (71.7) | 68 (64.2) | |||
| No | 13 (28.3) | 38 (35.8) | |||
| Tobacco Use 30 Days | 1.493 | 0.222 | |||
| Yes | 5 (10.9) | 20 (18.9) | |||
| No | 41 (89.1) | 86 (81.1) | |||
| Poly Substance Use 30 Days | N/A | 0.152 | |||
| Yes | 44 (95.7) | 92 (87.6) | |||
| No | 2 (4.3) | 13 (12.4) | |||
| Baseline: Comorbid Conditions | |||||
| Number of Active Medical or Psychiatric Problems | 2.22 | 0.028 | |||
| 1.52 (1.6) | 1.0 (1.3) | ||||
| Liver Enzyme | 3.367 | 0.067 | |||
| Any One Elevated | 16 (34.8) | 22 (20.8) | |||
| None | 30 (65.2) | 84 (79.2) | |||
| Hepatitis-C Infected | 0.046 | 0.831 | |||
| Yes | 9 (19.6) | 19 (18.1) | |||
| No | 37 (80.4) | 86 (81.9) | |||
| Past 30-day Injection Drug Use | 7.274 | 0.007 | |||
| Yes | 13 (28.3) | 11 (10.7) | |||
| No | 33 (71.7) | 92 (89.3) | |||
| Mean Scores on Internalizing Problems | 2.24 | 0.027 | |||
| 65.78 (9.1) | 61.08 (12.7) | ||||
| Mean Scores on Externalizing Problems | 1.2 | 0.231 | |||
| 59.59 (8.5) | 57.66 (9.8) | ||||
Note: Test statistic was Χ2 or Fisher-Exact test for categorical variables and Student t-tests for continuous variables. P values in bold indicate either statistical significance or values approaching statistical significance.
BUP = 12-week extended Buprenorphine/Naloxone therapy assignment; DETOX= 14-day buprenorphine/naloxone detoxification assignment; N/A = not available.