Fig. 6.

KLF4, p21 and β-catenin expression in human colon polyps. A panel of 25 human colon polyps was subjected to immunofluorescence staining as described in Materials and methods. Representative expressions of KLF4 (red) and β-catenin (green) immunofluorescence staining of (A) normal colonic epithelium and (B) colonic polyps (hyperplastic polyp and tubular adenoma). Nuclei were counterstained with DAPI (blue). Insets at the bottom right corner depict an enlarged area of the tumor indicating the extent of positive staining. (C) Representative immunofluorescence staining of KLF4 (red) and p21 (green) in a hyperplastic polyp and tubular adenoma. Nuclei were counterstained with DAPI (blue).