Figure 2.
JTE-013 inhibition of agonists in the S1PR2-CRE-bla assay. Dose response of S1P (A) or CYM5520 (B) on S1PR2- Cre-bla CHO cells was challenged with increasing concentrations of JTE-013 (● DMSO control, ■ 10 nM JTE-013, ▲ 30 nM JTE-013, ▼ 90 nM JTE-013).