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The effect of S1P and CYM5520 on intracellular cAMP levels in S1PR2 wild type- and triple mutant-expressed cells. Dose response of S1P (●) or CYM5520 (■) on intracellular content of cAMP in wild type- (A) and triple mutant- (B) S1PR2 expressed CHO cells was measured with luciferase activity.
