Table 2.
CHD ≤65 years old | All CHD | |||||
---|---|---|---|---|---|---|
Model 1 Subfractions excluded |
Model 2 HDL subfractions included |
Model 3 All subfractions included |
Model 1 Subfractions excluded |
Model 2 HDL subfractions included |
Model 3 All subfractions included |
|
Cigarettes (packs/day) | 1.32 (1.04, 1.67) P=0.02 |
1.26 (0.99, 1.59) P=0.06 |
1.19 (0.93, 1.51) P=0.17 |
1.33 (1.10, 1.60) P=0.003 |
1.26 (1.04, 1.52) P=0.02 |
1.17 (0.96, 1.42) P=0.15 |
BMI (kg/m2) | 0.99 (0.95, 1.04) P=0.73 |
0.97 (0.93, 1.01) P=0.19 |
0.96 (0.92, 1.01) P=0.11 |
1.00 (0.97, 1.04) P=0.92 |
0.99 (0.95, 1.02) P=0.44 |
0.98 (0.95, 1.02) P=0.27 |
Systolic BP (per 10 mmHg) | 1.11 (1.00, 1.22) P=0.06 |
1.10 (0.99, 1.21) P=0.07 |
1.11 (0.99, 1.22) P=0.07 |
1.15 (1.06, 1.24) P=0.001 |
1.15 (1.06, 1.24) P=0.001 |
1.16 (1.06, 1.25) P=0.001 |
Diastolic BP (per 10 mmHg) | 1.07 (0.89, 1.27) P=0.48 |
1.09 (0.91, 1.29) P=0.36 |
1.07 (0.90, 1.27) P=0.45 |
1.07 (0.93, 1.23) P=0.36 |
1.09 (0.94, 1.25) P=0.26 |
1.07 (0.92, 1.23) P=0.37 |
Cholesterol (per 10 mg/dl) | 1.09 (1.06, 1.12) P<10−8 |
1.09 (1.06, 1.12) P<10−8 |
1.00 (0.95, 1.06) P=0.88 |
1.07 (1.05, 1.10) P<10−8 |
1.07 (1.05, 1.10) P<10−9 |
0.97 (0.93, 1.02) P=0.32 |
LDL (per 10 mg/dl) | 1.05 (1.02, 1.08) P=0.001 |
1.06 (1.04, 1.09) P<10−6 |
||||
IDL (per 10 mg/dl) | 0.99 (0.90, 1.07) P=0.74 |
0.95 (0.89, 1.02) P=0.16 |
||||
Small VLDL (per 10 mg/dl) | 1.04 (0.99, 1.08) P=0.09 |
1.06 (1.03, 1.10) P=0.0003 |
||||
Large VLDL (per 10 mg/dl) | 1.00 (0.97, 1.03) P=0.82 |
0.99 (0.97, 1.02) P=0.57 |
||||
HDL3 (lowest quartile) | 1.49 (1.12, 1.97) P=0.007 |
1.36 (1.02, 1.81) P=0.04 |
1.48 (1.17, 1.86) P=0.001 |
1.29 (1.02, 1.63) P=0.03 |
||
HDL2 (lowest quartile) | 1.61 (1.21, 2.11) P=0.001 |
1.39 (1.04, 1.87) P=0.03 |
1.38 (1.10, 1.73) P=0.006 |
1.13 (0.89, 1.44) P=0.31 |
The hazard ratios from the multivariate models are adjusted for the model’s other variables in addition to age.