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A tissue-engineered cartilage construct in the shape of a human patellar cartilage layer, at day 35 of free-swelling culture is shown; the bottom platen is one of the two molds used for casting the chondrocyte-seeded agarose gel in the desired shape. Reprinted with permission from Hung CT, Lima EG, Mauck RL, et al: Anatomically shaped osteochondral constructs for articular cartilage repair. J Biomechanics 36:1853–1864, 2003.
