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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: Methods Mol Biol. 2012;849:157–167. doi: 10.1007/978-1-61779-551-0_11

Fig. 1.

Fig. 1

Schematic diagram illustrating the information contained in an intermittent-noncontact AFM scan of protein fibrils. Topography and Phase imaging layers of aggregates formed using a 1:1 mixture of rHaPrP wt and rHaPrP M206S–M213S under native conditions (9). 3D profile of the aggregates constructed with WSxM 5.0 after equalization and flattening.