Table 2.

Change in Vaginal Maturation Index (VMI), the primary variable, in the Controlled phase

		Change in VMI at visit C2
	n	Mean	SD	p Value
Intention-to-treat
Estriol–lactobacilli	44	35.2%	21.7%	< 0.001
Placebo	44	9.9%	14.5%
Per-protocol set
Estriol–lactobacilli	44	35.2%	21.7%	< 0.001
Placebo	43	10.2%	14.6%

SD, standard deviation