Table 4.
Association of alcohol drinking with PSA levels in controls
| Model 11 | Model 22 | Model 33 | |||||
|---|---|---|---|---|---|---|---|
| Exposure | Nco | RGM | (95% CI) | RGM | (95% CI) | RGM | (95% CI) |
| Binge drinking4 (Yes versus No) | 1,518 | 0.96 | (0.92; 1.00) | 0.98 | (0.94; 1.03) | 1.00 | (0.95; 1.05) |
| Drinking most days (Yes versus No) | 4,951 | 0.96 | (0.93; 0.98) | 0.95 | (0.93; 0.98) | 0.95 | (0.92; 0.98) |
| Categories of consumption | |||||||
| Nondrinker | 1,028 | 0.94 | (0.89; 0.99) | 0.97 | (0.92; 1.03) | 0.97 | (0.92; 1.03) |
| Special occasions only | 613 | 1.01 | (0.95; 1.08) | 1.02 | (0.95; 1.10) | 1.05 | (0.98; 1.13) |
| 1st third of weekly intake (0.1–9.8 units/week) | 3,805 | 1 | – | 1 | – | 1 | – |
| 2nd third of weekly intake (9.9–19.7 units/week) | 3,739 | 0.97 | (0.94; 1.01) | 0.98 | (0.95; 1.02) | 0.98 | (0.94; 1.02) |
| 3rd third of weekly intake (19.8–112 units/week) | 3,542 | 0.92 | (0.89; 0.95) | 0.92 | (0.88; 0.95) | 0.92 | (0.88; 0.96) |
1
Adjusted for age, center and date of recruitment and clinic visit.
2
Adjusted for variables in Model 1, and current BMI and measured systolic blood pressure.
3
Adjusted for variables in Model 2, plus history of diabetes, history of hypertension and history of hypercholesterolemia.
4
Regularly consuming 5+ units/occasion. Abbreviations PSA, prostate-specific antigen; RGM, ratio of geometric means; CI, confidence interval; Nco, number of controls.