Table 5.
Association of alcohol drinking with prostate cancer risk comparing cases and controls
| Model 11 | Model 22 | Model 33 | |||||
|---|---|---|---|---|---|---|---|
| Exposure | Nca/Nco | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) |
| Binge drinking4 (Yes versus No) | 272/1,518 | 0.93 | (0.81; 1.08) | 0.96 | (0.82; 1.13) | 0.99 | (0.84; 1.17) |
| Drinking most days (Yes versus No) | 897/4,951 | 0.95 | (0.87; 1.04) | 0.95 | (0.86; 1.05) | 0.94 | (0.84; 1.05) |
| Categories of consumption | |||||||
| Nondrinker | 185/1,028 | 0.90 | (0.75; 1.08) | 0.91 | (0.74; 1.11) | 0.79 | (0.64; 0.99) |
| Special occasions only | 123/613 | 1.02 | (0.83; 1.26) | 1.09 | (0.86; 1.37) | 1.05 | (0.82; 1.35) |
| 1st third of weekly intake (0.1–9.8 units/week) | 745/3,805 | 1 | – | 1 | – | 1 | – |
| 2nd third of weekly intake (9.9–19.7 units/week) | 689/3,739 | 0.94 | (0.84; 1.06) | 0.94 | (0.82; 1.06) | 0.91 | (0.80; 1.04) |
| 3rd third of weekly intake (19.8–112 units/week) | 644/3,542 | 0.92 | (0.82; 1.04) | 0.94 | (0.82; 1.07) | 0.91 | (0.79; 1.04) |
1
Conditional logistic regression—strata defined by age, center and date of recruitment and clinic visit—additionally adjusted for age as continuous variable
2
Additionally adjusted for current BMI and measured systolic blood pressure.
3
Additionally adjusted for variables in Model 2, plus history of diabetes, history of hypertension and history of hypercholesterolemia.
4
Regularly consuming 5+ units/occasion. Abbreviations OR, odds ratio; CI, confidence interval; Nca/Nco, number of cases/number of controls.