Table 1.
Patient/Treatment Characteristics
| Characteristics | Value or No. of Patients (%) |
|
|---|---|---|
| Age | median (range) | 64 (33-85) |
| Sex | Female | 41 (45.6%) |
| Male | 49 (54.4%) | |
| Disease stage | I | 6 (6.7%) |
| II | 5 (5.6%) | |
| III | 69 (76.7%) | |
| IV | 7 (7.8%) | |
| Limited | 3 (3.3%) | |
| Tumor histology | Squamous cell | 33 (36.7%) |
| Adenocarcinoma | 34 (37.8%) | |
| NSCLC NOS | 18 (20.0%) | |
| Other | 5 (5.6%) | |
| Karnofsky Performance Status score |
90-100 | 31 (34.4%) |
| 80 | 39 (43.3%) | |
| < 80 | 20 (22.2%) | |
| Smoking status | Current | 32 (35.6%) |
| Former | 50 (55.6%) | |
| Never | 8 (8.9%) | |
| BMI | median (range) | 25.7 (16.1-56.9) |
| Diabetes | Yes | 15 (16.7%) |
| No | 75 (83.3%) | |
| Radiation dose, Gy | median (range) | 70 (56-87.5) |
| Concurrent Chemotherapy | Yes | 81 (90.0%) |
| No | 9 (10.0%) | |
| Plexopathy before radiation | Yes | 13 (14.4%) |
| No | 77 (85.6%) | |
| Max. Brachial Plexus Dose, Gy |
median (range) | |
| 0.1 cm3 | 69.7 (56.2-81.8) | |
| 0.5 cm3 | 67.8 (51.1-81.3) | |
| 1.0 cm3 | 66.7 (47.9-81.0) | |
| 2.0 cm3 | 65.8 (43.8-80.5) | |
| Median dose to plexus, Gy | median (range) | 41.9 (10.0-96.0) |
| Plexopathy after radiation | Grade 0 | 76 (84.4%) |
| Grade 1 | 8 (8.9%) | |
| Grade 2 | 4 (4.4%) | |
| Grade 3 | 2 (2.2%) | |
| Time to plexopathy, mo | median (range) | 6.5 (1.4-37.4) |
Abbreviation: NSCLC NOS, non-small cell cancer not otherwise specified.