Table 3.

Multiple regression analysis in homozygous ΔF508 mice and WT littermates

Dependent variables	Independent variables	B	P value	R2 total model
Fat malabsorption (total)	Genotype (WT = 0)	−0.85	0.29	0.24
	Treatment (control = 0)	−1.0	0.25
	Gender (female = 0)	0.9	0.33
Fat malabsorption (saturated)	Genotype (WT = 0)	0.08	0.96	0.25
	Treatment (control = 0)	−2.3	0.13
	Gender (female = 0)	1.7	0.27
Fat malabsorption (unsaturated)	Genotype (WT = 0)	−1.0	0.19	0.24
	Treatment (control = 0)	−0.64	0.41
	Gender (female = 0)	0.74	0.34
Fecal bile salt excretion (total)	Genotype (WT = 0)	7.4	<0.001a	0.83
	Treatment (control = 0)	−5.1	0.006a
	Gender (female = 0)	−7.1	<0.001a
Fecal bile salt excretion (primary)	Genotype (WT = 0)	9.7	<0.001a	0.77
	Treatment (control = 0)	−4.0	0.06
	Gender (female = 0)	−5.9	0.01a
Fecal bile salt excretion (secondary)	Genotype (WT = 0)	−2.5	0.06	0.34
	Treatment (control = 0)	−1.1	0.37
	Gender (female = 0)	−1.2	0.34
Body weight	Genotype (WT = 0)	−3.2	0.004a	0.85
	Treatment (control = 0)	0.8	0.51
	Gender (female = 0)	8.1	<0.001a
	Gender × treatment	−5.3	0.01a
Area under the curve 1-13C-palmitin	Genotype (WT = 0)	−2.2	0.9	0.46
	Treatment (control = 0)	63.8	0.03a
	Gender (female = 0)	0.29	0.29
Area under the curve 1-13C-stearate	Genotype (WT = 0)	−8.4	0.77	0.33
	Treatment (control = 0)	55	0.09
	Gender (female = 0)	−3.5	0.9

B, unstandardized β coefficient; R², regression correlation coefficient; WT, wild-type.

^aStatistically significant.