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(A) Amino acid sequence of peptide TZ1C2. (B) Helical wheel representation of core layer packing within the second heptad of TZ1C2 in the staggered (left) and aligned (right) orientations. (C) Schematic representation of the registry shift that results from Cd(II) coordination to the cysteine residues of TZ1C2 (yellow: Cys-containing heptads and red: non-Cys-containing heptads).
