Figure 3. Expansion of effector (TEM) and central memory T-lymphocytes (TCM) in SAMP1 mice.
Flow cytometric analyses of SAMP1 and AKR mice MLN and spleen displayed expansion of effector TEM (CD44highCD62Llow) and central memory (CD44highCD62Lhigh) TCM CD4+ and CD8+ T-lymphocytes. Representative zebra plots gated on forward and side scatter, CD4+ and CD8+ were obtained from cells isolated from indicated organs at 5- and 20-weeks-of-age (n=4–6/strain).