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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: J Neurosci Methods. 2008 Oct 21;177(2):294–302. doi: 10.1016/j.jneumeth.2008.10.014

Fig. 4.

Fig. 4

Effect of pulse duration on α1β3γ2S GABAA receptor current kinetics. (a) Representative currents evoked by 400 μs (left) or 10 ms (right) pulses of 1 mM GABA applied to the same outside-out patch. (b) The effect of pulse duration on peak current amplitude. (c) Comparison of current activation during 400 μs (black) or 10 ms (grey) pulses of 1 mM GABA. (d) The effect of pulse duration on current rise time. (e) Comparison of current deactivation following 400 μs (black) or 10 ms (grey) pulses of 1 mM GABA. Currents were normalized to their amplitudes at the start of GABA washout. (f) The effect of pulse duration on the weighted time constant of deactivation. Filled bars above currents indicate duration of GABA exposure. **p < 0.01; ***p < 0.001.