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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: N Engl J Med. 2011 Jan 12;364(6):524–534. doi: 10.1056/NEJMoa1011893

Table 2.

Baseline Comparisons between Subjects Who Completed Follow-up and Those Who Withdrew, Withheld DNA Sample or Did Not View Results, or Were Lost to Follow-up.*

Variable Completed Follow-up Withdrew P Value Withheld Sample or Did Not View Results P Value Viewed Results but Lost to Follow-up P Value
No. of subjects 2037 55 NA 223 NA 1310 NA
Female sex (%) 55.3 67.3 0.08 53.4 0.58 49.3 0.001
Age (yr) 0.49 0.54 0.008
 Mean 46.7±12.0 45.6±13.6 46.2±11.2 45.6±11.6
 Range 19–85 21–71 22–82 19–85
Income ($) 0.02 0.02 0.009
 Median 100,000–149,999 100,000–149,999 100,000–149,999 150,000–199,999
 Modal 100,000–149,999 50,000–99,999 100,000–149,999 100,000–149,999
Median educational level Some postgraduate education Graduate of 4-yr college 0.04 Graduate of 4-yr college <0.001 Graduate of 4-yr college 0.001
White race (%) 84.2 63.6 <0.001 69.1 <0.001 76.6 <0.001
Scripps Health employee (%) 23.6 41.8 0.002 19.7 0.20 16.5 <0.001
Anxiety score§ 0.04 0.58 0.01
 Mean 35.2±9.6 37.8±9.5 35.8±10.2 36.2±10.0
 Median 34.0 37.0 35.0 35.0
 Range 20–72 22–57 20–65 20–74
Dietary fat score 0.02 0.97 0.34
 Mean 16.0±7.9 13.6±8.6 16.0±7.8 15.8±8.2
 Median 15.0 12.0 15.0 15.0
 Range 0–51 0–34 1–41 0–54
Exercise score 0.67 0.10 0.005
 Mean 28.6±23.0** 27.5±22.3 26.7±22.2†† 27.7±25.3‡‡
 Median 24.0** 23.8 21.0†† 22.1‡‡
 Range 0–246** 0–112 0–110†† 0–238 ‡‡
*

Plus–minus values are means ±SD. P values are for comparisons with the group of subjects who completed follow-up. P values for comparisons of sex, race, and employment by Scripps Health were calculated by means of Pearson's chi-square test; those for age by means of independent samples t-test; and those for income, education, and scores on assessments of anxiety, dietary fat intake, and exercise by means of the Mann–Whitney U test. NA denotes not applicable because no statistical test was performed.

Of the 89 subjects who withdrew, only 55 completed a baseline assessment.

Race was self-reported.

§

Anxiety was assessed with the 20-item subscale of the Spielberger State–Trait Anxiety Inventory; scores range from 20 to 80, with higher scores indicating higher anxiety. A score of 39 or less is considered to indicate low anxiety. A difference of 12 points or more on this measure is considered to indicate a reliable and clinically meaningful change.

Dietary fat intake was measured with the 17-item Block Dietary Fat Screener; scores range from 0 to 68, with higher scores indicating higher fat intake. A difference of 11 points or more on this measure is considered to indicate a reliable and clinically meaningful change.

Exercise and physical activity were measured with the Godin Leisure-Time Exercise Questionnaire; scores range from 0 to 246, with higher scores indicating greater physical activity (i.e., a greater number of metabolic-equivalent hours per week). A difference of 29 points or more on this measure is considered to indicate a reliable and clinically meaningful change.

**

A total of 1943 subjects were included in this category.

††

A total of 215 subjects were included in this category.

‡‡

A total of 1272 subjects were included in this category.