Table 1.
Baseline and procedural characteristics based on stent used for treating bare-metal in-stent restenosis.
| Characteristics | Drug-eluting Stent (n = 362) | Bare-metal Stent (n = 344) | p-value |
|---|---|---|---|
| Age, years | 64±11 | 63±12 | 0.21 |
| Male, % | 271 (75) | 229 (67) | 0.02 |
| Body mass index | 30±5 | 30±6 | 0.35 |
| Heart rate | 70±14 | 71±13 | 0.25 |
| Left ventricular ejection fraction | 51±10 | 51±11 | 0.67 |
| Risk factors, % | |||
| Family history of premature coronary disease | 110 (30) | 138 (40) | 0.007 |
| Cigarette smoking | 38 (11) | 42 (12) | 0.47 |
| Diabetes mellitus | 144 (40) | 160 (47) | 0.07 |
| Insulin dependent diabetes mellitus | 47 (13) | 67 (20) | 0.02 |
| Non-insulin dependent diabetes mellitus | 95 (26) | 88 (26) | 0.84 |
| Medical history, % | |||
| Prior myocardial infarction | 197 (54) | 191 (56) | 0.77 |
| Peripheral arterial disease | 53 (15) | 43 (13) | 0.41 |
| Prior coronary artery bypass surgery | 159 (44) | 127 (37) | 0.06 |
| Stroke or transient ischemic attack | 44 (12) | 38 (11) | 0.65 |
| Chronic obstructive pulmonary disease | 45 (12) | 35 (10) | 0.34 |
| Clinical presentation, % | |||
| Acute myocardial infarction | 8 (2) | 11 (3) | 0.42 |
| Unstable angina | 170 (47) | 210 (61) | 0.0002 |
| New York Heart Association class, % | |||
| 3 | 46 (13) | 11 (3) | <0.0001 |
| 4 | 31 (9) | 5 (1) | <0.0001 |
| Medications, % | |||
| Aspirin | 362 (100) | 344 (100) | 1.00 |
| Clopidogrel | 362 (100) | 344 (100) | 1.00 |
| Heparin | 111 (31) | 192 (56) | <0.0001 |
| Glycoprotein IIb/IIIa inhibitors | 107 (30) | 258 (75) | <0.0001 |
| Beta-blockers | 129 (36) | 114 (33) | 0.49 |
| Angiotensin converting enzyme inhibitors | 182 (50) | 134 (39) | 0.003 |
| Statins | 298 (82) | 183 (53) | <0.0001 |
| Location of culprit lesion, % | |||
| Proximal left anterior descending artery | 51 (14) | 67 (19) | 0.06 |
| Mid or distal left anterior descending artery | 160 (44) | 167 (49) | 0.25 |
| Left circumflex artery | 158 (44) | 141 (41) | 0.48 |
| Right coronary artery | 153 (42) | 177 (51) | 0.01 |
| Angiographic characteristics | |||
| Reference vessel diameter, mm | 3.0±0.4 | 2.9±0.5 | <0.0001 |
| Stent length, mm | 37.7±21.8 | 20.2±15.8 | <0.0001 |
| Chronic total occlusion, % | 30 (8) | 12 (3) | 0.007 |
| Saphenous vein graft, % | 59 (16) | 48 (14) | 0.39 |
| Multivessel intervention | 104 (29) | 135 (39) | 0.003 |
| Number of diseased vessels, % | |||
| 1 | 225 (62) | 147 (43) | <0.0001 |
| 2 | 96 (27) | 122 (35) | 0.01 |
| 3 | 41 (11) | 75 (22) | 0.0002 |
| American College of Cardiology lesion score, % | |||
| A | 13 (4) | 24 (7) | 0.04 |
| B1 | 55 (15) | 83 (24) | 0.003 |
| B2 | 115 (32) | 112 (33) | 0.82 |
| C | 179 (49) | 125 (36) | 0.0004 |
| Procedural success, % | 356 (98) | 334 (97) | 0.27 |