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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: Nature. 2012 Jun 28;486(7404):496–501. doi: 10.1038/nature11142

Figure 3. Nucleosome sequence preferences.

Figure 3

a. Position-dependent frequencies of AA, AT, TA, or TT dinucleotides in the chemical map, by quartiles of NCP score/noise ratio. b, Comparison of dinucleotide frequency between the chemical map and the MNase 1 map. The chemical map shows significantly stronger AA/AT/TA/TT dinucleotide signals suggesting an improved center alignment of nucleosomal DNA. c, 5-mer preferences of nucleosomes (left) and linker DNA regions (right) in chemical map compared to the MNase 1 map, colored by numbers of A or T nucleotides.