Table II.
Levels of cytokines and immunoglobulins following surgery.
Group | Before anesthesia | 4 h after induction of anesthesia | 1 day after surgery | 2 days after surgery | |
---|---|---|---|---|---|
TNF (pg/ml) | Group C | 1.51±0.41 | 1.71±0.16 | 1.61±0.22 | 1.4±0.38 |
Group A | 2.53±0.43 | 2.82±0.16 | 3.09±0.24 | 3.82±0.4 | |
Group S | 3.44±0.41 | 2.75±0.16 | 3.15±0.22 | 2.99±0.38 | |
IL-10 (pg/ml) | Group C | 1.28±0.21 | 4.83±1.32a | 3.97±1.04a | 1.66±0.53 |
Group A | 2.53±0.22 | 3.16±1.4 | 7.18±1.1a | 5.69±0.56a | |
Group S | 2.82±0.21 | 3.04±1.32 | 6.36±1.04a | 4.01±0.53a | |
IL-8 (pg/ml) | Group C | 11.45±5.67 | 10.9±1.67 | 17.48±46.61 | 12.36±60.33 |
Group A | 8.96±6.52 | 16.73±1.76 | 111.52±49.14ab | 228.61±63.59ab | |
Group S | 38.08±15.67 | 13.54±1.67 | 119.18±46.61ab | 174.28±60.33ab | |
IgM (g/l) | Group C | 1.47±0.11 | 1.16±0.1 | 1.29±0.13 | 1.38±0.12 |
Group A | 0.19±0.11 | 0.19±0.11 | 0.19±0.14 | 0.18±0.13 | |
Group S | 0.32±0.11 | 0.26±0.1 | 0.3±0.13 | 0.26±0.12 | |
IgA (g/l) | Group C | 4.16±0.41 | 2.77±0.37a | 2.89±0.35a | 3.25±0.31a |
Group A | 0.61±0.43 | 0.64±0.39b | 0.65±0.37b | 0.63±0.32 | |
Group S | 1.05±0.41 | 0.88±0.37b | 0.98±0.35b | 0.71±0.31 | |
IgG (g/l) | Group C | 0.53±0.08 | 0.47±0.07 | 0.44±0.08 | 0.45±0.07 |
Group A | 0.42±0.08 | 0.42±0.08 | 0.42±0.09 | 0.41±0.08 | |
Group S | 0.46±0.08 | 0.46±0.07 | 0.46±0.08 | 0.46±0.07 |
Values are expressed as the mean values ± SD.
Compared with before anesthesia, there was a significant difference within the group, (P<0.05);
compared with group C, there was significant difference between group C and group A or group C and group S (P<0.05).
TNF, tumor necrosis factor; IL, interleukin.