Table II.
Comparison of HGF and MCP-1 mRNA expression in renal tissue of each group (mean ± SD).
| Groups | n | HGF mRNA/GAPDH mRNA | MCP-1 mRNA/GAPDH mRNA |
|---|---|---|---|
| Control | 10 | 0.1765±0.0121 | 0.7877±0.1059 |
| Model | 9 | 0.1524±0.0088 | 4.5371±0.3158a |
| High-dose | 9 | 0.2292±0.0215a,b | 2.3954±0.1792a–d |
| Low-dose | 10 | 0.1986±0.0149a,b | 2.9647±0.1476a,b |
| Fosinopril | 10 | 0.3389±0.1340a,b | 1.5336±0.1340a,b |
a
P<0.01, compared with the control group;
b
P<0.01, compared with the model group;
c
P<0.01, high-dose group compared with the low-dose group;
d
P>0.05, high-dose group compared with the fosinopril group. GAPDH, glyceraldehyde 3-phosphate dehydrogenase; HGF, hepatocyte growth factor, MCP-1, monocyte chemotactic protein-1.