Table 1.
vehicle | Angiotensin I
|
||||
---|---|---|---|---|---|
control | temocapril | olmesartan | |||
Body weight (g) | baseline | 180 ± 1 | 179 ± 1 | 180 ± 1 | 177 ± 2 |
week 4 | 315 ± 7 | 320 ± 8 | 297 ± 5 | 310 ± 5 | |
Kidney weight (g) | 2.2 ± 0.1 | 2.7 ± 0.1* | 2.3 ± 0.1# | 2.2 ± 0.1# | |
Kidney weight / body weight ratio (× 10−3) | 7.1 ± 0.1 | 8.5 ± 0.2* | 7.6 ± 0.1# | 7.1 ± 0.2# | |
Urinary protein/creatinine ratio | 3.3 ± 0.4 | 14.3 ± 2.2* | 6.2 ± 0.6# | 5.7 ± 1.1# |