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. Author manuscript; available in PMC: 2013 Sep 30.
Published in final edited form as: Biomaterials. 2012 Apr 22;33(21):5247–5258. doi: 10.1016/j.biomaterials.2012.03.076

Fig. 3.

Fig. 3

Effect of HA presence and size on hypertrophic chondrocytes: biosynthesis. Both GAG and collagen content were significantly higher at day 14 for the micro-HA group (*p < 0.05, n = 5). Corresponding histology reveals strongly positive matrix staining for the micro-HA group (Alcian Blue for GAG and Picrosirius Red for collagen, 10x, bar = 200 µm, day 14, n = 2). More specifically, strongly positive collagen II staining and minimal collagen I staining, was observed for all groups (immunohistochemistry, 10x, bar = 200 µm, Day 14, n = 2).