Table 1. Cell cycle distribution of non-sub-G1 cells after panobinostat treatment of neuroblastoma cell lines.

Cell	Cell	Panobinostat (nM)
line	Cycle	0	5	10	20	40	80
	G0/G1	71.76±0.31	ND	68.79±0.64	67.36±0.41	55.02±0.81	51.46±0.48
SK-N-SH	S	17.04±0.20	ND	16.08±0.15	16.65±0.22	27.33±0.91	29.69±0.62
	G2/M	11.61±0.07	ND	15.27±0.36	16.02±0.41	16.91±0.77	18.59±0.41
	G0/G1	67.10±0.49	ND	62.77±0.28	55.00±1.36	29.72±0.51	43.76±0.28
SK-N-BE(2)	S	17.58±0.21	ND	19.08±0.74	23.81±0.69	30.72±0.22	29.00±0.76
	G2/M	15.51±0.28	ND	18.30±0.53	22.00±0.37	39.61±0.28	27.62±0.69
	G0/G1	60.95 ±0.35	73.55 ±0.23	57.05 ±0.32	42.99 ±0.21	37.65 ±0.25	ND
SK-N-AS	S	22.14 ±0.38	13.50 ±0.19	16.02 ±0.19	16.84 ±0.57	12.87 ±0.26	ND
	G2/M	17.07 ±0.13	13.32 ±0.11	27.60 ±0.37	40.78 ±0.44	50.19 ±0.37	ND
	G0/G1	54.81±0.38	42.05±0.58	31.60±0.38	31.39±1.82	32.25±0.83	ND
SK-N-DZ	S	30.40±0.32	35.35±0.20	34.31±1.28	29.63±0.89	27.00±0.71	ND
	G2/M	14.75±0.03	22.34±0.52	31.56±1.30	35.62±1.08	38.68±1.36	ND

Note: SK-N-AS, SK-N-DZ, SK-N-SH or SK-N-BE(2) cells were treated with variable concentrations of panobinostat for 48 h. Cell cycle progression was determined by PI staining and flow cytometry analyses. The data are presented as means ± standard errors of triplicates from one representative experiment. ND, not determined.