Table 1. Reproducibility of [11C]FLB 457 and amphetamine in plasma.
| Parameter | Mean | BSSD | BSSD CV | WSSD | WSSD CV | VAR + SD | ICC |
|---|---|---|---|---|---|---|---|
| [11C]FLB 457 fp (%) | 0.38 | 0.05 | 0.14 | 0.06 | 0.15 | 23.0% ± 18.6% | -0.05 |
| [11C]FLB 457 Clearance (L/h) | 69.72 | 14.33 | 0.21 | 8.85 | 0.13 | 23.7% ± 15.3% | 0.45 |
| Amphetamine level 0 min (ng/mL) | 87.34 | 11.83 | 0.14 | 4.11 | 0.05 | 8.1% ± 7.2% | 0.78 |
| Amphetamine level 45 min (ng/mL) | 76.60 | 11.22 | 0.15 | 3.45 | 0.05 | 7.1% ± 6.6% | 0.83 |
| Amphetamine level 90 min (ng/mL) | 73.82 | 11.08 | 0.15 | 4.16 | 0.06 | 9.8% ± 8.8% | 0.75 |
Values are the mean of 10 subjects with each value measured twice. BSSD CV = between subject standard deviation coefficient of variation, WSSD CV = within subject standard deviation coefficient of variation, VAR = test/retest variability, ICC = intraclass correlation coefficient.