Table 2. Reproducibility of post-amphetamine [11C]FLB 457 total distribution volume (VT, mL cm-3).
Region | Mean | BSSD | BSSD CV | WSSD | WSSD CV | VAR + SD | ICC |
---|---|---|---|---|---|---|---|
Cerebellum | 3.90 | 0.51 | 0.13 | 0.37 | 0.09 | 14.7% ± 11.1% | 0.32 |
Medial Temporal Lobe | 8.45 | 1.55 | 0.18 | 0.79 | 0.09 | 14.9% ± 11.1% | 0.59 |
Anterior Cingulate Cortex | 6.97 | 1.15 | 0.16 | 0.68 | 0.10 | 14.7% ± 13.0% | 0.48 |
Dorsolateral prefrontal Cortex | 5.96 | 1.32 | 0.22 | 0.54 | 0.09 | 14.4% ± 10.7% | 0.72 |
Orbital Frontal Cortex | 7.09 | 1.49 | 0.21 | 0.72 | 0.10 | 16.8% ± 11.7% | 0.62 |
Medial Prefrontal Cortex | 6.36 | 1.06 | 0.17 | 0.54 | 0.09 | 13.5% ± 11.1% | 0.59 |
Temporal Cortex | 9.64 | 2.30 | 0.24 | 0.90 | 0.09 | 14.8% ± 11.3% | 0.73 |
Parietal Cortex | 6.13 | 1.61 | 0.26 | 0.54 | 0.09 | 14.0% ± 10.8% | 0.80 |
Occipital Cortex | 5.81 | 1.59 | 0.27 | 0.53 | 0.09 | 14.7% ± 10.7% | 0.80 |
Values are the mean of 10 subjects with each value measured twice. BSSD CV = between subject standard deviation coefficient of variation, WSSD CV = within subject standard deviation coefficient of variation, VAR = test/retest variability, ICC = intraclass correlation coefficient.