Table 3. Reproducibility of post-amphetamine [11C]FLB 457 binding potential relative to plasma concentrations (BPP, mL cm-3).
Region | Mean | BSSD | BSSD CV | WSSD | WSSD CV | VAR + SD | ICC |
---|---|---|---|---|---|---|---|
Medial Temporal Lobe | 4.55 | 1.20 | 0.26 | 0.45 | 0.10 | 16.1% ± 11.1% | 0.75 |
Anterior Cingulate Cortex | 3.07 | 0.74 | 0.24 | 0.32 | 0.11 | 16.9% ± 14.5% | 0.68 |
Dorsolateral prefrontal Cortex | 2.06 | 0.91 | 0.44 | 0.19 | 0.09 | 14.8% ± 9.3% | 0.92 |
Orbital Frontal Cortex | 3.19 | 1.08 | 0.34 | 0.38 | 0.12 | 21.7% ± 13.4% | 0.78 |
Medial Prefrontal Cortex | 2.46 | 0.69 | 0.28 | 0.18 | 0.08 | 12.4% ± 11.1% | 0.87 |
Temporal Cortex | 5.74 | 1.90 | 0.33 | 0.56 | 0.10 | 15.3% ± 11.3% | 0.84 |
Parietal Cortex | 2.23 | 1.21 | 0.54 | 0.18 | 0.08 | 13.9% ± 9.8% | 0.96 |
Occipital Cortex | 1.91 | 1.17 | 0.61 | 0.19 | 0.10 | 17.2% ± 9.8% | 0.95 |
Values are the mean of 10 subjects with each value measured twice. BSSD CV = between subject standard deviation coefficient of variation, WSSD CV = within subject standard deviation coefficient of variation, VAR = test/retest variability, ICC = intraclass correlation coefficient.