Table 4. Reproducibility of post-amphetamine [11C]FLB 457 binding potential relative to non specific uptake (BPND, unitless).
Region | Mean | BSSD | BSSD CV | WSSD | WSSD CV | VAR + SD | ICC |
---|---|---|---|---|---|---|---|
Medial Temporal Lobe | 1.16 | 0.26 | 0.22 | 0.06 | 0.05 | 6.8% ± 5.8% | 0.91 |
Anterior Cingulate Cortex | 0.78 | 0.15 | 0.19 | 0.03 | 0.04 | 6.9% ± 5.2% | 0.91 |
Dorsolateral prefrontal Cortex | 0.52 | 0.19 | 0.37 | 0.02 | 0.03 | 5.4% ± 4.9% | 0.98 |
Orbital Frontal Cortex | 0.81 | 0.21 | 0.27 | 0.05 | 0.06 | 11.1% ± 7.9% | 0.90 |
Medial Prefrontal Cortex | 0.63 | 0.15 | 0.24 | 0.02 | 0.03 | 4.3% ± 4.3% | 0.97 |
Temporal Cortex | 1.45 | 0.36 | 0.25 | 0.05 | 0.03 | 3.9% ± 3.9% | 0.97 |
Parietal Cortex | 0.55 | 0.26 | 0.47 | 0.01 | 0.03 | 4.2% ± 2.8% | 0.99 |
Occipital Cortex | 0.47 | 0.26 | 0.56 | 0.02 | 0.05 | 6.7% ± 4.9% | 0.99 |
Values are the mean of 10 subjects with each value measured twice. BSSD CV = between subject standard deviation coefficient of variation, WSSD CV = within subject standard deviation coefficient of variation, VAR = test/retest variability, ICC = intraclass correlation coefficient.